Our research group works at the intersection of cell biology, synthetic biology, and disease, with active projects in the field of exosome biogenesis, exosome engineering, cell engineering, and re-wiring intracellular signaling pathways to study and treat human disease
Exosome Biogenesis
Exosomes are small secreted vesicles of ~100 nm in size that play critical roles in human health and disease. Our lab seeks to understand the molecular mechanisms that mediate protein/vesicle budding.
Exosome Engineering
Our laboratory uses our understanding of exosome biogenesis and cell engineering to create recombinantly engineered exosomes for use as probes and tools in disease research.
New Systems for Cell Engineering
Our lab is developing new selectable marker genes, and using them to create protein expression and cell tarnsgenesis (ProtECT) systems that select for the highest-possible level of recombinant protein expression.
We seek motivated scientists who want to answer fundamental questions in cell biology and human disease, and to translate that knowledge into new research tools and therapeutics. Although we prefer candidates with a strong background in biochemistry and cell biology, attitude is everything.
Graduate Students
We welcome PhD and Master’s students from across the globe. To discuss entry into our programs, or potential rotation projects, send an email to Steve that includes your c.v. and research interests.
Post-Doctoral Fellows
We are particularly interested in post-doctoral candidates with high enthusiasm and a strong record of independent research. If interested, please send an email to Steve that includes your c.v. and research interests. .
Undergraduates
Undergraduates with an enthusiasm for research are also welcome in our lab. If you’re interested, please send an email to Steve that includes your c.v. and all that you hope to gain from a lab research experience.